The TRAIL to a new era in cancer therapies: welcome to the age of immunotherapy

By LifETIME CDT Student: Aoibhin Sheedy (NUI Galway)   Immunotherapy is a promising approach for breakthrough therapies in the treatment of ovarian cancer, but there needs to be a robust investigation into suitable targets and delivery methods to solidify its true value for patients and clinicians. Ovarian cancer is the fourth leading cause of death due

Can biomaterials pave the way to more advanced screening of cancer drugs?

By LifETIME CDT Student: Chanelle McGuinness (University of Glasgow)   Bone marrow is a complex organ that is home to numerous cell populations. Haematopoietic stem cells (HSCs) in the bone marrow are responsible for specialising and becoming all blood cell types – a process known as haematopoiesis. They are also the basis for HSC transplants for patients

Using droplet fluidics to mimic hypoxia and nutrient deprivation conditions of tuberculosis; an original bubble act

By LifETIME CDT Student: Antonia Molloy (Aston University)   Tuberculosis (TB) is the world’s leading cause of death by infectious disease. As a young researcher learning immunology, I was particularly fascinated by the ability of Mycobacterium tuberculosis (the causative agent of TB disease) to manipulate the hosts’ own immune system for its survival. Instead of

Cell’s mechanosensitivity: The key in label-free diagnosis

By LifETIME CDT Student: Anna Maria Kapetanaki (University of Glasgow) Since the very beginning of life creation, sensation has played a determinant role in species evolution. We, as complex animals, experience the world around us using our senses (vision, hearing, olfaction). This ability has been vital for our species survival as it allows us to

Interview with our Sustainability Representatives

Laboratory work has a significant impact on the environment, ranging from plastic waste and lack of recycling to energy consumption. Due to our CDT having students who occupy so many labs across the partner universities, we have made it our mission to reduce our carbon footprint by starting a sustainable labs working group. Our goal

Of mice and men: human ‘joint-on-a-chip’ looks to solve the puzzle of joint diseases

By LifETIME CDT Student: Abigail Wright (University of Birmingham) Osteoarthritis (OA) refers to a group of debilitating diseases that prevent joints from working correctly. This is the main cause of adult disability. Despite this, we are unable to treat the disease and most patients find pain management ineffective. This is due to our limited understanding how

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