By LifETIME CDT Student: Conor Robinson (University of Glasgow) The population of Haematopoietic Stem Cells (HSCs) present at birth will be responsible for repopulating the body with all blood and immune cells until death. If someone is dealt a bad hand and their HSCs are damaged or mutate, this can result in many blood disorders like …
By LifETIME CDT Student: Theodora Rogkoti (University of Glasgow) The bone marrow is a specialised environment containing a complex set of cellular, biochemical, and physical signals that all work together to form the so-called “bone marrow niche”. These niche-specific cues regulate the localisation, function, and movement of Hematopoietic stem cells (HSCs), the cells responsible for developing …
By LifETIME CDT Student: Santino Chander (Aston University) The eye is our window to the world. It is a vital organ that allows us to see our surroundings and loved ones. However, like all biological tissue, it can become compromised – such as through infection or a disorder such as dry eye disease. Often these compromises …
By LifETIME CDT Student: Viswanath Vittaladevaram (NUI Galway) Like a defensive line in a football field, the blood-brain barrier protects central nervous system against pathogens and toxins and regulates the passage of many cells and substances into nervous tissue. A vast majority of disorders associated with central nervous system is linked with blood brain barrier …
By Emma Lardner, Operations Manager at the University of Birmingham and lifETIME CDT Administrator for Birmingham. Earlier this month, lifETIME CDT (Engineered Tissues for Discovery, Industry and Medicine) and the Healthcare Technologies Institute held a Sustainability Showcase event which brought together academics, researchers and students from within the CDT but also from the wider Scientific community …
By LifETIME CDT Student: Juda Milvidaite (University of Glasgow) Cells, tissues, and organs are fragile – they cannot survive outside of a living body for long. When we need to store or transport biological samples from cancer patients for further research or personalised screening of therapies, we freeze the samples down. Yet, the cycles of …